在 intron 1 中插入了 loxP 立场,随后在 neomycin 抗性基因座周围包含了 FRT 立场,并在 intron 2 中再加入了一个 loxP 立场。随后通过 Flp 介导的重组,去除了 neo 驱动元件。(来源:J:283325)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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