Amyotrophic Lateral Sclerosis 1 (ALS1)

Alias:
Amyotrophic Lateral Sclerosis
Als
Lou Gehrig Disease
Charcot Disease
Amyotrophic Lateral Sclerosis Type 1
Amyotrophic Lateral Sclerosis, Susceptibility to
Als1
Familial Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Lou Gehrig's Disease
Fals
Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis with Dementia
Dementia with Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial
Sclerosis, Lateral, Amyotrophic, Type 1
Als - [amyotrophic Lateral Sclerosis]
Sclerosis, Lateral, Amyotrophic
Progressive Atrophic Paralysis
Spinal Progressive Amyotrophy
Motor Neuron Disease, Bulbar
Amyotrophy Lateral Sclerosis
Amyotrophic Sclerosis
Amyotrophic Paralysis
Wasting Paralysis
Wasting Palsy
Mnd
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基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
肌萎缩侧索硬化症1型,也称为肌萎缩侧索硬化症,与额颞叶痴呆症和/或肌萎缩侧索硬化症1型和额颞叶痴呆症有关,症状包括背痛、头痛和疼痛。与肌萎缩侧索硬化症1型有关的重要基因是SOD1(超氧化物歧化酶1),其相关通路/超通路包括神经科学和物理化学特性以及毒性相关通路。在该疾病的背景下,已提到的药物有美西律和大麻二酚。附属组织包括骨、肢和脊髓,相关表型为肌萎缩侧索硬化症和全身性肌肉无力。
Related ID:
MESH:D000690
ICD11:1982355687

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
常隐
常显
成年期
1-9/100000
503
5218
342

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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