Rare Disease
Amyotrophic Lateral Sclerosis 1 (ALS1)
Alias:
Amyotrophic Lateral Sclerosis
Als
Lou Gehrig Disease
Charcot Disease
Amyotrophic Lateral Sclerosis Type 1
Amyotrophic Lateral Sclerosis, Susceptibility to
Als1
Familial Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Lou Gehrig's Disease
Fals
Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis with Dementia
Dementia with Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial
Sclerosis, Lateral, Amyotrophic, Type 1
Als - [amyotrophic Lateral Sclerosis]
Sclerosis, Lateral, Amyotrophic
Progressive Atrophic Paralysis
Spinal Progressive Amyotrophy
Motor Neuron Disease, Bulbar
Amyotrophy Lateral Sclerosis
Amyotrophic Sclerosis
Amyotrophic Paralysis
Wasting Paralysis
Wasting Palsy
Mnd
Neuronal diseases
Respiratory diseases
Muscle diseases
Oral diseases
Mental diseases
Basic Information
Amyotrophic Lateral Sclerosis 1, also known as amyotrophic lateral sclerosis, is related to frontotemporal dementia and/or amyotrophic lateral sclerosis 1 and frontotemporal dementia, and has symptoms including back pain, headache and pain. An important gene associated with Amyotrophic Lateral Sclerosis 1 is SOD1 (Superoxide Dismutase 1), and among its related pathways/superpathways are Neuroscience and Physico-chemical features and toxicity-associated pathways. The drugs Mexiletine and Cannabidiol have been mentioned in the context of this disorder. Affiliated tissues include Bone, Limb and spinal cord, and related phenotypes are amyotrophic lateral sclerosis and generalized muscle weakness
Basic Information
Inheritance
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Prevalence
Related Gene
Disease Model
Reference
MALACARD
Medical Symptom
Even among those with the same illness, each patient's condition and symptoms are unique. To provide patient-centered medical care, medical professionals must carefully evaluate individual differences between patients. This involves thorough assessment of medical details when diagnosing and developing treatment plans. To achieve personalized and maximally effective care, practitioners refer to the latest research and standards of care to tailor treatment strategies for each patient.
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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
Gene & Mutation
Diseases are frequently associated with anomalies or mutations in certain genes. These genes and mutations can disrupt cellular functioning and induce physiological imbalances, resulting in illnesses. In-depth research on illness genes and mutations can help us better understand disease etiology and give new ideas and approaches for disease prevention, diagnosis, and therapy.
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Gene
Function
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Drugs
Gene target medications are a novel form of treatment that can alter genes or proteins while also blocking disease processes. It precisely detects and chooses target proteins in order to induce therapeutic effects. Target medications are categorized into several groups based on disease causes and molecular foundation, and numerous ways are employed to treat illnesses.
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Phase
Disease Model
The mouse disease model refers to the manipulation of the mouse genome through gene editing and other techniques, enabling it to carry a specific disease gene or lack an important gene. This provides an experimental platform for researching the mechanism of disease occurrence, drug development, and treatment efficacy.
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Name
MGI
Related Gene
Strain of Origin
Publications
References
Disease literature reviews provide a wide spectrum of research findings and clinical data, giving vital information for our comprehensive understanding of illnesses. By researching this material, we may gain a better understanding of the illness's pathophysiology and treatment strategies, as well as give a scientific foundation for disease prevention and management.
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PMID
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Comparison
BioGPT