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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Mir27a
tm1.1Bge
Alias:
MiR-27a
fl
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基础信息
表型特征
文献报道
在miR-27a基因的编码区域两侧插入了LoxP位点。通过Flp介导的重组,在生殖细胞中移除了与A耐药性 cassette共插入的元件。(来源:J:345171)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
7594053
C57BL/6N
Targeted
插入
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--
--
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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