这个小鼠品系对Cre和FLP重组酶敏感。当Cre/FLP双重组时,细胞会表达H2B-TagBFP(蓝色核)、sfGFP(绿色整体细胞)和synaptophysin-tdTomato(红色突触前接触)。它可以通过转基因传递或病毒方式,通过Cre和FLP的双重表达来区分细胞类型。双重组后,目标细胞会在细胞的三个区域显示荧光:蓝色核、绿色整体细胞和红色突触前接触。(来源:J:94077)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Endonuclease-mediated
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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