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中文
CRISPR/Cas9技术通过sgRNA5'-TGACATCGCTGTTATCCAAG-3设计，产生了一个65bp的内含子2到外显子3的缺失。这个缺失阻止了外显子3的剪接，可能导致产生包含Dnase1活性位点的4、5或6号外显子的替代剪接，进而产生框架移位突变和早止密码子。(来源：J:345011)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
