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中文
CRISPR/cas9通过针对外露loop 1的指导RNA进行的重组产生了多处DNA变异，导致RRE在第278位起始位置的3个氨基酸被替换为AAA。这种突变干扰了Furin的切割位点，影响了蛋白质的加工(来源：J:344557)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
