这个等位基因是在Jackson实验室通过电穿孔Cas9蛋白和两个引导序列(CGAGAACCTTTTCTAAATCT, GTCTCTCTGAAACACACCGA)产生的,导致了5号染色体(Chr5)100,480,147-100,480,565一段419bp的缺失,具体位置是GRCm38/mm10基因组。这个变异移除了ENSMUSE00001057239的外显子。(来源:J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count