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中文
这个小鼠品系是由CRISPR-Cas9在C57BL/6NCrl小鼠中进行定点突变产生的，导致D1821A/D1822A变异（在人类同源物编码的e肽的D1841A/D1842A位点对应）。额外的silent突变也被引入。突变的exon38现在这样读取：(5')gtggctgaagggccagcaggaggacaaacaggacacagatgtccactatcactccctcacgggggagggcaacttcaactggagatacctcttccccttcgactacctagcggccgaagagaagatcgttatgtccaaaaaggagtctatgttctcctgggatgagacggagtacaagatccctgcgcggctcaccctgcagatctgggacgctgaTcacttctcggctgCTgCcttcctgg(3')（来源：J:344236）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
