这个等位基因是在Jackson实验室通过电穿孔Cas9蛋白和两个引导序列(ACTCCAAAAGAAGTCTATCA, AACAGACTCTTTCTGACTTA)产生的,导致了3号染色体(Chr3)9,264,341-9,265,623一段1,283bp的缺失,这个缺失区域包含了基因ENSMUSE00000769877的整个外显子(来自文献J:188991)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
基因内删除
不确定
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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