The targeting construct replaced the coding region of the gene with a Cre recombinase open reading frame followed by an FRT-flanked neomycin cassette. Flp-mediated recombination removed the neo cassette. (J:343535)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count