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中文
CRISPR/cas9基因编辑技术被用来在含有Atxn1tm1Hzo突变体（154Q到175Q的自发三核苷酸扩张）的囊胚中引入p.K772T（赖氨酸替换为丝氨酸，AG转为CC）突变和额外的同义突变（改变PAM序列以提高编辑效率并便于基因型鉴定）。小鼠中的p.K772T突变与人类中的p.S776A位点相似。（来源：J:343335）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
