Log In|Sign Up
中文
在exon 52的第5477位，酪氨酸(Trp)的密码子(TAC)被替换成了阿尔法(Ala)，变异为p.Y5477A，这是通过sgRNA和ssODN模板，利用CRISPR/Cas9技术实现的。这个改变产生了编码肽功能丧失的酶型版本。(来源：J:342639)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
