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中文
在第13外显子的lysine编码位置392(AAA)被替换为arginine(AGA)，通过sgRNA和ssODN模板，使用了CRISPR/Cas9技术。这个突变发生在编码肽的DNA结合区域，与影响糖尿病严重程度的同一个人类功能获益性变异(NM_011486.3:c.1175A>G)相同。(来源：J:342716)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
