CRISPR/cas9介导的重组产生了一个2个氨基酸的替换(苯丙氨酸18和苏氨酸19被替换为亮氨酸和异亮氨酸),这干扰了与Transducin-like Enhancer of Split蛋白的相互作用。(来源:J:342149)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
核苷酸替换
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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