ENU诱变导致了17号外显子的T807位置由TGG转换为AGG,即一个T到A的替换,产生了p.W807R的变异。这种变异与接受OVA/铝佐剂刺激后血清中总IgE和OVA特异性IgE水平的增加有关。(来源:J:296761)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
单点
半显性
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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