在第7个内含子插入了含氨苄青霉素抗性基因座(FRT)和一个loxP位点,然后在第8个内含子插入了另一个loxP位点。通过Flp介导的重组,去除了neo cassette,留下了一个有条件突变体,其第8个外显子被敲除。(来源:J:336403)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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