CRISPR/cas9基因编辑通过指导RNA(GGGATATTTTAGGAGCCTGA, ATATTTTAGGAGCCTGAGGG, ATTCCTTCGCCTACATCCAG, TTGCCACTGGATGTAGGCGA)剪切并替换小鼠exon 3,用一个含loxP内切酶座的野生型exon 3插件。这个exon 3的缺失变异是一个插入/缺失突变。参考了转录本Slc37a4-201(ENSMUST00000165839.3)来确定exon编号和引导序列。来源:(J:94077)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count