T2A-CreERT2 cassette被插入到Mlc1基因exon12的内含子末端原停用密码子的上游,FRT引导的Neo选择 cassette位于3' UTR下游116bp的位置。在靶向载体中的Neo cassette在胚胎干细胞克隆扩增时被去除。(来源:J:341452)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129 x C57BL/6
Targeted
插入
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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