这个等位基因是通过Cre介导的对Igh区域的890kb基因序列的删除产生的,该区域带有lox71/loxP的标记。删除后保留了由Pgk1启动子驱动的布拉希霉素抗性基因。(来源:J:341427)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
插入,基因内删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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