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中文
在exon 3的第130位，酪氨酸(Trp)编码被替换为阿尔法-亮氨酸(Ala)，用sgRNA(靶向ATGTACACATAGATCTTAGC)和ssODN模板通过CRISPR/Cas9技术实现，变异位于编码肽的4HB区域，影响了Atrx的结合(来源：J:340029)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
