The transgene was generated using pcD-SRa-derived expression vector, pME18S, which is composed of the simian virus 40 (SV40) ori, SV40 early promoter and a part of the long terminal repeat of human T-cell leukemia virus type 1, HCV cDNA (full-length translated gene , 3' (missing X) (human), and SV40 polyA signal. (J:104881)