这个靶向构建设计用于在Pld2基因的Exon11上游插入一个loxP位点,随后是FRT标记的neo cassette,再在Exon12下游插入另一个loxP位点。通过Flp酶介导的重组会去除neo cassette,而Cre介导的重组会剪切掉Exons11和12。来源:(J:260679)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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