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中文
这个等位基因是在表型遗传学中心通过向细胞中注入Cas9 mRNA，配以带有spacer序列AGCATCTGACACTGAGTAAG的指导RNA，以及编码c.1376_1377CA>TC(替换为p.S459F)这一非同义变异的单链寡核苷酸，以及c.1368C>T(无功能的p.A456)的沉默突变，来产生的。这些改动旨在破坏protospacer adjacent motif（PAM）序列（来源：J:339146）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
