Log In|Sign Up
中文
在exon 4的CGGArginine第134位被替换为GAA，编码为p.R134E，这是通过sgRNA(针对CACAGGCCACCTTCCCACAGCGG)和ssODN模板，利用CRISPR/Cas9技术实现的。这个变异等同于人类在侵蚀性关节炎和骨髓炎患者中发现的p.K131E变异（来源：J:338375）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
