CRISPR/cas9 endonuclease-mediated genome editing is used to insert hemagluttin-tagged human PACS1 cDNA, followed by an IRES and a GFP reporter under the control of the widespread CAG promoter into the Gt(ROSA)26Sor locus. A loxP-flanked neomycin STOP precedes the PACS1 sequence. The GFP is too low to be detected and was only used for PCR genotyping. (J:338950)