在exon 2的上游265bp位置插入了FRT-flanked新霉素筛选 cassette,然后在exon 2的下游169bp位置插入了loxP位点。通过flp介导的重组,去除了新霉素筛选 cassette。exon 2通过cre介导的重组被删除了。(来源:J:338919)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count