CRISPR/cas9基因编辑通过引导crRNA[GGAGGAACTCTTCGCACACT],在Gata3基因的3' UTR内插入了内源性启动子/citrine黄色荧光序列。参考的Gata3转录本是Gata3-201(ENSMUST00000102976.4),用于识别exon编号和指导序列(位置J:307783)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
插入
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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