将iCre重组酶基因,由小鼠Acrv1启动子序列驱动,并带有hygromycin抗性基因座,两侧带有翻转子识别靶位点的cDNA插入到Gt(ROSA)26Sor定位序列中。经生殖传递后,这些小鼠与Flp剔除线杂交,以去除hygromycin抗性基因座。(来源:J:338406)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
Targeted
插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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