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中文
在exon 11的359位甘氨酸（GAA）被替换为赖氨酸（AAA），即p.E359K，同时在exon 13的3' UTR插入了含loxP序列的诺卡因抗性基因座。随后通过Cre介导的重组移除了这个neo cassette。这种变异对编码肽的稳定性产生了负面影响。（来源：J:304821）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
