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中文
CRISPR/Cas9技术产生了一个GAA替换为GGC的改变，导致第1371位的谷氨酸被甘氨酸取代（p.E1371G），位于丝氨酸结合域。同时，还引入了多个无义编码变异来阻断Cas9的靶标。这与人类的p.E1458G变异相关，该变异与心律失常和结构重塑有关（来源：J:338515）。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
