这种转基因小鼠表达了一种融合基因APTTC,由人类胎盘碱性磷酸酶的截短部分与TTC(tetanus毒素C片段)组成。这种小鼠可用于在具有tetacycline调控转录激活器(tTA)的特定神经元中诱导APTTC的表达,作为反向遗传标记物(来源:J:337810)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6CrSlc
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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