CRISPR/Cas9技术针对exon 2的起始翻译位点进行编辑,产生了246bp的缺失。 Western blot结果显示,纯合子大脑中没有检测到蛋白质(来源:J:337720)
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CRISPR/Cas9 technology targeting the translation start site in exon 2 generated a 246 bp deletion. Western blot analysis confirmed absence of protein in the brain of homozygotes. (J:337720)