将一个带有诺卡因抗性基因、内含子序列(IRES)和mCitrine标记的YFP报告基因插入了3' UTR。1.9kb增强子(Enh)序列的5'和3'端的同源臂被deltaEnh-hygro载体替换,通过在Bcl11btm1.1Evrline(J:260615)和Bcl11btm1Hykuline(J:290296)中携带的ES细胞中进行同源重组,以在一个拷贝上消除增强子。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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