这种在exon 1a的ATG起始密码子上的自发胸腺嘧啶替换为胞嘧啶,导致exon 3成为下一个内切起始密码子,预测会形成一个起始缺失变异,影响到第一个锌指域。Rorb1转录在大脑和视网膜中的表达显著增加,而Rorb2转录在视网膜中的量显著减少。(来源:J:337403)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Applicable
Spontaneous
单点
隐性
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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