这个转基因载体包含了CAG启动子(CMV-IE增强子,鸡β-actin启动子,兔β-球蛋白的基因组DNA),P1噬菌体的loxP位点,大肠杆菌的氯霉素甲酰转移酶(CAT)基因,以及小鼠Dll4的cDNA。Dll4基因在Cre介导的重组去除含floxed-CAT基因后会被表达。(来源:J:104881)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count