这个转基因载体包含了CAG启动子(CMV-IE增强子,鸡β-actin启动子,兔β-珠蛋白的基因组DNA),大肠杆菌的氯霉素甲酰转移酶(CAT)基因,poly A序列,以及小鼠Nkx2.5的cDNA,以及P1噬菌体的loxP位点。通过Cre介导的cat基因剔除后,小鼠基因开始表达。(来源:J:104881)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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