Rr426^em1Axvi

The Tbx5 lung enhancer, located downstream of the gene, was targeted with sgRNAs (targeting ACTGGAAATCAAGACTGGGCAGG, GGAAACTGGAAATCAAGACTGGG, GCATGCTGGGGTAAGCCCGAGGG and GCTGGGGTGCCAAGCCCAGAGGG) using CRISPR/Cas9 technology, resulting in an 843 bp deletion (chr5:120239700-120240542 (GRCm39)). (J:335096)