这个转基因表达的是一个由人Akt的myristoylated激活形式和一个突变雌激素受体的配体结合域融合而成的融合蛋白,由CAG启动子控制。Akt-Mer还连接了IRE-SGFP,可以通过GFP荧光来监测Akt-Mer的表达。(来源:J:125544)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x DBA
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1
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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