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中文
通过CRISPR/Cas9技术，我们用sgRNA和ssODN模板创建了两个突变，位置在chr6:31197455的G>A和chr6:31197457的A>T。这两个突变发生在内含子1，移除了exon1的剪接起始点，从G-GTA变成了G-ATT，导致这个等位基因的转录几乎完全被抑制。（来源：J:324861）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
