基于小鼠BAC RP23-318M13构建了靶向载体。在包含HS1-HS5(HS5-1)敏感性区域序列的序列下游插入了loxP位点。上游插入了由loxP位点引导的诺卡因抗性基因座。调节区域位于Pcdha基因簇下游,调控其基因的表达。(来源:J:277249)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
插入
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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