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中文
将酪氨酸密码子792(tat)替换为苯丙氨酸(ttyt)，通过sgRNA(靶向acatgtcatcaagttgtatggg)和ssODN模板，使用CRISPR/Cas9技术实现了这一变异。这个突变等同于人类的p.y791f变异，与霍奇金斯综合症(HSCR)关联。(来源：J:325770)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
