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中文
通过sgRNA和ssODN模板，利用CRISPR/Cas9技术将arginine的87位密码子(CGC)替换为 cysteine( TGC)，产生了c.259C>T的变异，即p.R87C。这个变异等同于人类West syndrome关联的p.Arg87Cys突变(引用：J:335442)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
