转基因包含一个BAC(RP23-341J5)元件,它在大肠杆菌中通过同源重组改造,将CreERT2编码序列插入Vsx1基因的起始密码子附近,总共有160kb的Vsx1基因座区域被修改。获得了9条奠基品系,其中471号品系由于重组率高而被建立并用于研究(来源:J:322776)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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