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中文
通过sgRNA和ssODN模板，使用CRISPR/Cas9技术，Serine的第18位(AGC)被替换为Isoleucine(ATC)（p.S18I），第20位(AGC)被替换为Alanine(GCT)（p.S20A）。这些改变阻止了对高度保守残基的磷酸化。(来源：J:327336)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
