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中文
CRISPR/cas9基因编辑工具通过在第262位的外显子2上产生一个由精氨酸替换为异亮氨酸的突变，即D/A替换。这个改变将细胞中参与DNA活动所需的天冬氨酸残基变为无活性的异亮氨酸。相关的crRNA和tracrRNA序列为：crRNA#1针对262位的D/A，序列是(AGCCACTCTGCAGGGAGTCG)，crRNA#2针对3号外显子的D/A，序列是(ACATGAACCCCTGATTGACG)，tracrRNA。信息来源：(J:335226)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
