靶向载体被设计用于将维纳斯黄绿荧光蛋白(cDNA)的编码插入基因的C末端。一个由loxP位点标记的诺卡因抗性元件,连同Cre自剪接转基因,被插入到exon 2的上游。这个元件使得在杂合体雄性生殖细胞中整套元件能够被剔除。(来源:J:335214)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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