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中文
在exon 6的第398位，作为丝氨酸的密码子(甘氨酸-天冬氨酸-天冬氨酸, GAT)被替换成了天冬酰胺(AAT)，这通过sgRNA(靶向CCGCGCYCGATTGCATTCGCTAC)和ssODN模板，应用了CRISPR/Cas9技术。这个突变等同于人类的单核苷酸多态性(SNP)rs16969968，它与尼古丁和阿片类依赖相关(p.D398N)。来源：J:342737
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
