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中文
捐赠者通过体内基因敲除和转座异位重组，在小鼠7C染色体上构建了与人类15q13.3区域同源的1.4兆碱基的重复或缺失。通过基因靶向，LoxP位点被插入到小鼠基因组中，以在Cre介导的重组后用来复制或删除该区域。在将LoxP等位基因整合到动物体内之前，通过Flp/FRT介导的重组去除了可选择标记。参考文献：(J:94077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
