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中文
通过传统的ES细胞定向策略和同源重组，将T2A肽和改良型Cre重组酶(iCre)的开放阅读框插入Npff基因第3外显子的最后一个氨基酸和终止密码子之间。通过与携带FRT座的germline Flpe小鼠杂交，移除了带有阳性选择标记(Puromycin抗性)的片段。(来源：J:334879)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
